Bring the quinoa and water or chicken stock to a boil in a saucepan over high heat.
Reduce heat to medium-low, cover, and simmer until the quinoa is tender and the water has been absorbed, about 15-20 minutes. Set aside to cool.
Heat oven to 350 F.
Heat the olive oil in a skillet over medium heat. Stir in the onion, carrot and bell pepper. Sauté until the onion has softened and turned translucent, about 5 minutes.
Add the garlic and cook for another minute; remove from heat to cool.
In a large bowl, stir the turkey, cooked quinoa, cooked veggies, tomato paste, cayenne, onion and garlic powder, 2 tablespoons Worcestershire, eggs, salt and pepper until well combined. The mixture will be very moise.
Shape into a loaf on a parchment or foil lined rimmed baking sheet.
Combine the brown sure and 2 teaspoons Worcestershire in a small bowl. Rub the paste over the top of the meatloaf.
Bake in the preheated oven until no longer pink in the center, about 50 minutes.
An instant-read thermometer inserted into the center should read at least 160 degrees F.
Let the meatloaf cool for about 10 minutes before slicing and serving.